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This Scientist Is Building Custom Gene-Editing Tools

Scribe Therapeutics Highlights Data Underpinning its Comprehensive Strategy Targeting Key Lipid Drivers of ASCVD at American Heart Association (AHA) Scientific Sessions 2025

November 17, 2025

Scribe Therapeutics Highlights Data Underpinning its Comprehensive Strategy Targeting Key Lipid Drivers of ASCVD at American Heart Association (AHA) Scientific Sessions 2025

November 17, 2025

Epigenetic editors are a gentler form of gene editing

February 24, 2025

The Economist

Epigenetic editors are a gentler form of gene editing

February 24, 2025

CRISPR 2.0, the Next Generation

June 21, 2024

Aspen Ideas: Health

CRISPR 2.0, the Next Generation

June 21, 2024

The Age of CRISPR: Engineering the Future of Genetic Medicine

February 23, 2024

TEDxBerkeley

The Age of CRISPR: Engineering the Future of Genetic Medicine

February 23, 2024

All Stories

News

CRISPR Partnerships Propel Precision Medicine

February 20, 2024

CRISPR Medicine News

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Press Release

CRISPR Partnerships Propel Precision Medicine

February 20, 2024

CRISPR Medicine News

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News

A CRISPR collaboration compilation

February 19, 2024

Nature

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Press Release

A CRISPR collaboration compilation

February 19, 2024

Nature

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News

Scribe Therapeutics Picks Cholesterol-Lowering As First In Vivo Gene Target

February 7, 2024

Scrip

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Press Release

Scribe Therapeutics Picks Cholesterol-Lowering As First In Vivo Gene Target

February 7, 2024

Scrip

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News

A road to survival

January 17, 2024

ASBMB Today

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Press Release

A road to survival

January 17, 2024

ASBMB Today

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Press Release

Scribe Therapeutics Expands In Vivo Collaboration with Sanofi to Second Target

January 3, 2024

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Press Release

Scribe Therapeutics Expands In Vivo Collaboration with Sanofi to Second Target

January 3, 2024

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Press Release

Scribe Therapeutics to Present at the 42nd Annual J.P. Morgan Healthcare Conference

January 2, 2024

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Press Release

Scribe Therapeutics to Present at the 42nd Annual J.P. Morgan Healthcare Conference

January 2, 2024

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News

Small Enzymes, Giant Leaps: CRISPR’s Next-Generation Approach to Genetic Diseases

August 5, 2024

BioSpace

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News

Future of Epigenetic Medicine

July 22, 2024

FutureBites

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News

CRISPR 2.0, the Next Generation

June 21, 2024

Aspen Ideas: Health

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News

CRISPR technology’s next wave: Eight companies to watch in 2024

June 20, 2024

Labiotech

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News

Top Five Privately Held Gene Editing Therapy Companies

May 31, 2024

Genetic Engineering & Biotechnology News

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News

Women @ RopesTalk: Conversation with Svetlana Lucas, Scribe Therapeutics

May 22, 2024

Ropes & Gray

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Press release

Scribe Therapeutics Presents Late-Breaking Preclinical Data Supporting STX-1150, a Clinical-Stage Epigenetic Silencing Therapy Designed to Achieve Years of LDL-C Lowering After a Single Dose

May 28, 2026

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Press release

Scribe Therapeutics Achieves Regulatory Clearance to Initiate First-in-Human Clinical Study of STX-1150 for LDL-C Reduction

May 21, 2026

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Press release

Scribe Therapeutics Reports Preclinical Data at ASGCT 2026 Demonstrating Enhanced Potency and Specificity of Engineered CRISPR Technologies for Epigenetic Silencing and Gene Editing

May 18, 2026

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Press release

Scribe Therapeutics to Highlight Engineered CRISPR Platform Advances and Lead Cardiometabolic Pipeline at ASGCT and EAS Congress 2026

April 30, 2026

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Press release

Scribe Therapeutics Achieves Second Success Milestone for In Vivo Program in Collaboration with Eli Lilly and Company

February 17, 2026

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Press release

Scribe Therapeutics Projected to Enter the Clinic in Mid-2026 with STX-1150, a PCSK9-targeting CRISPR Epigenetic Silencing Therapy for Durable LDL-C Reduction

January 20, 2026

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Publications and presentations

Publication

Engineered Allosteric Control Enhances Specificity and Potency of CRISPR-CasX-based Epigenetic Repressors

January 14, 2026

bioRxiv

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Publication

Single particle charge detection mass spectrometry enables molecular characterization of lipid nanoparticles and mRNA packaging

May 18, 2025

Journal of Controlled Release

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Publication

CasX enzymes comprise a distinct family of RNA-guided genome editors

February 4, 2019

Nature

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Publication

Efficient genome editing in the mouse brain by local delivery of engineered Cas9 ribonucleoprotein complexes

May 1, 2017

Nature Biotechnology

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Publication

Targeted gene knock-in by homology-directed genome editing using Cas9 ribonucleoprotein and AAV donor delivery

March 2, 2017

Nucleic Acids Research

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Publication

Profiling of engineering hotspots identifies an allosteric CRISPR-Cas9 switch

June 1, 2016

Nature Biotechnology

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Publication

Multi-reporter selection for the design of active and more specific zinc-finger nucleases for genome editing

January 7, 2016

Nature Communications

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Publication

Enhanced homology-directed human genome engineering by controlled timing of CRISPR/Cas9 delivery

December 15, 2014

eLife

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Publication

Programmable RNA recognition and cleavage by CRISPR/Cas9

December 11, 2014

Nature

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Publication

MicroRNA-mediated switching of chromatin-remodelling complexes in neural development

July 30, 2009

Nature

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