In The News
October 8, 2020

CRISPR-Based ALS Treatment Being Developed by Scribe and Biogen

Genetic Engineering & Biotechnology News – Best known for her pioneering work in the discovery of CRISPR, Jennifer Doudna, PhD, professor at the University of California, Berkeley, doesn’t stop or, it seems, even slow down. As of yesterday morning, Doudna can add “accept Nobel Prize” to her to-do list as she, along with Emmanuelle Charpentier, PhD, was awarded the 2020 Nobel Prize in Chemistry.

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October 8, 2020

Scribe, Biogen Partner to Develop Gene Therapy for ALS, Other Neurological Diseases

ALS News Today – Founded by the scientists who originally invented CRISPR, Scribe has developed novel, custom-CRISPR tools, using a technology called X-Editing. This advanced gene-editing platform has greater editing activity and higher specificity, meaning that it can edit the target gene with greater precision than other CRISPR tools currently available.

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October 7, 2020

Scribe Therapeutics emerges with $20M, Biogen pact to clear CRISPR hurdles

FierceBiotech – CRISPR evolved in bacteria as a form of “genetic vandalism,” as George Church, Ph.D., puts it, to fend off pathogens. That means it works very well in bacteria but runs into various obstacles when researchers try to put it to work in humans. Jennifer Doudna’s latest CRISPR company plans to surmount those hurdles with an entirely new CRISPR platform that does not rely on molecules found in nature.

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October 6, 2020

Starting with Biogen deal in ALS, Scribe planning a new chapter in CRISPR story

BioWorld – Scribe Therapeutics Inc., another CRISPR-based genome editing firm out of the Jennifer Doudna stable, launched with $20 million in series A funding and a deal with Biogen Inc. in amyotrophic lateral sclerosis (ALS), which brings in another $15 million up front and up to $400 million in development and commercial milestones.

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October 6, 2020

Scribe: engineering CRISPR’s next generation

BioCentury – Scribe is carving out a new space in the gene editing landscape with a next-generation version of the technology from Jennifer Doudna’s lab that substitutes engineered CRISPR enzymes for their natural counterparts.

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October 6, 2020

CRISPR startup Scribe Therapeutics lands big Biogen deal

San Francisco Business Times – Hoping to take the CRISPR genome-editing tool to the next level of drug development, startup Scribe Therapeutics Inc. said Tuesday that it landed a potential $400 million neurodegenerative disease deal with Biogen Inc.

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